The Vinogradov Laboratory

Department of Psychiatry, University of Minnesota

 

What is the TRuSST Study?

 

TRuSST is a research study conducted by Sophia Vinogradov, M.D. in the Department of Psychiatry at The University of Minnesota-Twin Cities. TRuSST is investigating whether computerized training might help people with schizophrenia lessen their symptoms and learn new thinking and problem-solving skills.

 

Where is the TRuSST Study?

 

Participants will visit the Vinogradov Lab in the Department of Psychiatry at the University of Minnesota to complete questionnaires and a series of cognitive measures. They will then be assigned to receive computerized social cognition exercises, or a similar amount of computer games, for 8 to 12 weeks. These can be completed at home or in the clinic.

 

Who Can Participate?

 

Study participants should:

•Have a diagnosis of schizophrenia as defined by DSM-V criteria

•Be between the ages of 18 and 65 years old

•Be in good general health

•Have been clinically stable for at least 8 weeks

•Been on stable medication for at least 6 weeks before starting the study

•Have learned English before the age of 12

•Have not had a history of severe substance use within the past 3 months

•Have not been treated within 5 years with a computer-based cognitive training program from Posit-Science

Why Participate in TRuSST?

 

Although you may or may not directly benefit from participating in this research, the information that you provide will help health professionals better understand how computerized training might be used in the future to help people with schizophrenia lessen their symptoms and to learn new thinking skills and problem-solving abilities.

 

Through your participation in the research study, you could receive up to $415 for participating in the study! You’ll be paid $25 for each of the seven in-person assessment appointments, as well as $10 if transportation is required. You will also be paid $5 for each day you participate in the training program for the full 45 minutes. Finally, you will receive a $10 bonus for every 10 sessions of training completed, up to $40.

 

What will happen if I decide to participate?

 

• Research staff will conduct an eligibility interview and ask you some questions about your symptoms and how you are feeling. During a second visit, you will complete some questionnaires and a series of cognitive measures. This will take about 4 hours and can be completed in one or two visits.

 

• If you are eligible, and you choose to participate, you will be assigned by chance to receive either computerized social cognition exercises or a similar amount of computer games. You will complete your first training session with a coordinator.

 

• Over the next eight to twelve weeks, you will spend 45 minutes per day, three to five days per week completing exercises, for a total of 30 hours. After the first 15 hours of training and after 30 hours of training, you will be asked to complete the same questionnaires and measures from the beginning of the study. These will take 4 hours and can be completed in one or two visits.

 

• Research staff will contact you weekly by phone to follow your progress.

 

How long will the study take?

 

If you decide to participate in this study you will be actively involved in the research study intervention for approximately 16-20 weeks.

 

How do I join?

To see if you are eligible, please call (612) 626-7886, or email trusst@umn.edu

 

                                            Vinogradov Research Lab

                                                      Department of Psychiatry, University of Minnesota

TRuSST

Computerized Social Cognition Training for Schizophrenia